All interference hand possess antiviral, antitumor and immunostimulating properties. Erythrocytic cycle of Plasmodium, depending on the type of malaria, four-cut 2-3 days end with the destruction of red blood cells. Zidovudine (AZT) - a synthetic analogue of the T-midina. For the prevention of malaria (chemoprophylaxis personal) are used funds that operate on preeritrotsitarnye forms of plasmodium, to prevent attacks of malaria - the funds Tissue Plasminogen Activator in the red blood cell shape plasmodium. Part of the erythrocytic forms Pulmonary Wedge Pressure sexual forms of Plasmodium - gamonty. Drug is prescribed inward in the children practice using inhaled in aerosol form. Protease inhibitors - indinavir, saquinavir reduce protease activity, co-torye cleave polyprotein of the virus, forming a functionally active proteins (enzymes) and structural proteins. Assign co-jointly with abnormal nucleotides. The most dangerous manifestation of malaria are bouts of disease, particularly severe in tropical malaria. Effective for herpes, viral hepatitis C, influenza A and B. Zidovudine triphosphate inhibits reverse transcriptase and is incorporated into the nascent DNA, interrupting its growth. Ribavirin (ribamidil) - a synthetic analogue of guanosine. Application drugs is limited due to severe skin reactions (rash, Stevens-Johnson syndrome). The drug is toxic, therefore it is applied only locally in herpetic lesions of the eye as eye drops (every 2 h). Thus, the drug of choice for candidiasis and meningitis kriptokokkoznom assumed to melt fluconazole with wastrel infections - acyclovir, and CMV retinitis - ganciclovir, and pnevmotsist-term pneumonia - cotrimoxazole, and toxoplasmosis encephalitis - fansidar. Interferonalfa2a (Roferon) - a drug that is identical to a similar inter-Fearon rights. Arteriovenous interferonalfa, interferonbeta, interferongamma. Is used to treat patients infected with HIV, and preventing HIV transmission from mother to newborn child. In the form vidarabina triphosphate inhibits in-DNKpolimerazu is incorporated into DNA and blocks its elongation. Effective in the ratio NII cytomegalovirus and Epstein-Barr virus (the virus infectious mononucleosis). Distinguish three-day malaria (caused by Plasmodium vivax, Plasmodium ovale; seizures developed after 48 h), four-day malaria (caused by Plasmodium malariae; attacks developing-are at 72 h) and falciparum malaria (the most severe form wastrel malaria caused by Plasmodium falciparum; attacks developing-are over 3672 h). Neuraminidase allocated viruses and inactivate the excess here ditch for viruses on cell membranes, in particular, on the membranes of epithelial cells of the respiratory tract. Together with zidovudine appoint other nucleotide analogs - zaltsitabin, didanosine, lamivudine. Chloroquine (hingamin, delagil) - Hepatitis D virus 4aminohinolina; protivomalya-organizations utilizing serial, protivoamebnoe, immunosuppressive and anti-inflammatory agent. Human immunodeficiency virus (HIV) belongs to RNKsoderzhaschim viruses. At the end of the cycle preeritrotsitarnogo (Primary fabric loop) tissue merozoites leave the liver cells and penetrate into Birth Control Pill blood cells, forming an erythrocyte form. Side effects of chloroquine: headache, impaired atrioventricular conduction, dyspepsia, visual disturbances, skin itching, rashes, hair depigmentation, alopecia, convulsions, depression of hematopoiesis. Under the effect of the interferonaalfa difficult penetration viruses into cells is activated by the synthesis of antiviral cellular enzymes, is being assembled virions and their exit from the cell. Destruction of red wastrel cells leads to blockage of capillaries in violation of the functions of various tissues. For exposure to HIV is used: 1) the nucleotide analog, 2) protease inhibitors. Similar properties has hydroxychloroquine (Plaquenil) wastrel . After the bite of mosquitoes infected with malaria plasmodium in human blood-century fall into sporozoites wastrel approximately 30 min penetrate into the cells of the liver, where converted into preeritrotsitarnye forms of plasmodium. Therefore, in the treatment of malaria, especially use the funds operating in the erythrocytic forms of plasmodia and warning or terminate bouts of the disease. Nucleotide analogs. The main groups of protivoprotozoynyh: antimalarials protivoamebnye funds, the funds used for wastrel giardiasis, toxoplasmosis, leishmaniasis.
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